Fig 3
HE-Et reduces size of AB-10-stained plaque in the area including cerebral cortex and hippocampus of APP/PS1 mice. a. The representative images of ThS (green)- and AB-10 (red)-stained plaques (60 for each) selected in order of decreasing size from the area include the cerebral cortex and hippocampus of vehicle- and HE-Et-treated APP/PS1 mice. b. A scatter plot of ThS- and AB-10-stained areas from representative samples with vehicle and HE-Et treatments (solid lines: linear regression lines; dashed lines: 95 % confidence intervals; R 2 = 0.8224 for vehicle and R 2 = 0.9079 for HE-Et). c. The levels of soluble and insoluble Aβ1-42 determined by ELISA. The results are the mean ± S.D. Significant differences between treated and control (Veh) groups are indicated by *, p < 0.05