Fig. 6

NAD + −induced AP shortening in the presence of phospholipases inhibitors. a relative APD90 at the moment of maximal AP shortening induced by 10 μM NAD+ in normal conditions and in the presence of PLC inhibitor U73122 (0.1 μM) or PLD inhibitor FIPI (0.1 μM). APD90 is expressed in % of control APD90. * - significant effect of NAD+, p < 0.05, Wilcoxon test. & - significant difference between the columns, p < 0.05, Mann–Whitney test. b, c representative traces of APs before and during NAD+ application in the presence of U73122 (b) or FIPI (c)