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Fig. 7 | Journal of Biomedical Science

Fig. 7

From: Mechanisms of inflammatory responses and development of insulin resistance: how are they interlinked?

Fig. 7

C-C motif chemokine receptor 5 (CCR5) promotes obesity-induced inflammation and IR. Recently, it has been found that the expression of CCR5 and its ligand MCP-1 is significantly increased in white adipose tissues (WAT) and its accumulation is increased in adipose tissue macrophages (ATM) in WAT of obese mice and provides a novel link between inflammation and IR in adipocytes by stimulating the production of various pro-inflammatory cytokines and chemokines. Adopted from Ota [51]

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Journal of Biomedical Science

ISSN: 1423-0127