Fig. 3From: Aldehyde dehydrogenase 2 activation and coevolution of its εPKC-mediated phosphorylation sitesSensitivity of the non-phosphorylatable and phosphomimetic ALDH2 mutants to 4HNE inactivation. Enzyme activity of each of the T185, S279 and T412 single phosphorylation mutant (A or E) with or without incubation with 50 μM of 4HNE. All enzyme activities are presented as a percentage of the no 4HNE treatment for each of the mutantBack to article page