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Table 1 Overview of blood lipid and lipoprotein changes in response to ApoE deficiency and/or western-type diet

From: Crossroads between peripheral atherosclerosis, western-type diet and skeletal muscle pathophysiology: emphasis on apolipoprotein E deficiency and peripheral arterial disease

 

ApoE-/- ND vs. WT ND

ApoE-/- WD vs. WT WD

Total Cholesterol

↑ 3–7fold [48, 52, 54, 287]

↑ 2–18fold [48, 52, 54, 99, 100, 287]

VLDL/IDL

↑ 10fold [52, 54, 79, 95]

↑ 10–30fold [47, 52, 54, 95]

LDL

↑ 4-14fold [58, 79, 95]

↑ 3–14fold [47, 54, 95]

TGs

↑ 0–4fold [48, 52, 54, 58, 100, 287]

↑ 0–2fold [48, 52, 54, 58, 100, 287]

HDL

↓ 0–1.7fold [15, 48, 58, 79, 95]

↓ 0–2fold or ↑3fold [48, 52, 95, 98, 103]

  1. Abbreviations: HDL High-density lipoprotein, LDL Low-density lipoprotein, ND Normal chow diet, VLDL/IDL Very low-density lipoprotein/Intermediate density lipoprotein, TGs Triglycerides, WD Western-type diet, ↑Increase, ↓Decrease
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Journal of Biomedical Science

ISSN: 1423-0127