Fig. 5From: H558R, a common SCN5A polymorphism, modifies the clinical phenotype of Brugada syndrome by modulating DNA methylation of SCN5A promoters a The rate of methylation was lower in 13 of 16 methylation site. The methylation ratio of the SCN5A gene, according to the presence or not of H558R. b The rate of methylation was lower in patients with H558R than in those without (0.7 ± 0.2% vs. 1.6 ± 0.1%, P = 0.004). All data are indicated by box plots and mean ± standard errorBack to article page