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Table 3 Differentially expressed miRNAs in mesenchymal subtype

From: Molecular subtyping of nasopharyngeal carcinoma (NPC) and a microRNA-based prognostic model for distant metastasis

 

Limma analysis

Cox regression analysis

ID

logFC

adj.P.Val

Hazard ratio (95% CI)

P value

ebv-miR-BART11-5p

−1.54706

2.16E-25

0.9777 (0.8187242–1.167488)

0.803

hsa-let-7a

−1.40183

8.66E-25

0.963 (0.7880834–1.176745)

0.711

hsa-let-7b

− 1.06179

2.16E-25

0.9471 (0.7233448–1.239976)

0.691

hsa-let-7d

−1.23859

2.46E-62

0.789 (0.5750843–1.081624)

0.141

hsa-let-7f

−1.1923

2.45E-57

0.759 (0.5521583–1.042009)

0.0867

hsa-let-7i

−1.3304

1.87E-56

0.735 (0.5547504–0.9745582)

0.0329*

hsa-miR-103

−1.21743

1.79E-43

0.87 (0.6585442–1.148594)

0.328

hsa-miR-1246

−1.08753

3.66E-27

0.857 (0.6564593–1.117855)

0.251

hsa-miR-1248

−1.34498

1.76E-38

0.89 (0.6972987–1.136929)

0.352

hsa-miR-1308

−1.21742

6.61E-23

0.98 (0.7887421–1.218035)

0.857

hsa-miR-141

−1.16218

1.26E-28

0.752 (0.5827463–0.9715151)

0.0291*

hsa-miR-142-3p

−1.0139

3.21E-30

0.55 (0.397994–0.7602394)

0.000166*

hsa-miR-16

−1.12108

1.17E-16

0.879 (0.7166531–1.078863)

0.217

hsa-miR-1973

−1.22079

3.55E-19

1.0439 (0.8511332–1.280275)

0.678

hsa-miR-1975

−1.03043

1.01E-11

1.0092 (0.8323964–1.223649)

0.925

hsa-miR-19b

−1.02683

1.09E-30

0.902 (0.6693412–1.216764)

0.5

hsa-miR-200b

−1.08776

1.26E-28

0.799 (0.6070927–1.050777)

0.106

hsa-miR-21

−1.67241

7.01E-37

0.99486 (0.820039–1.206952)

0.958

hsa-miR-23a

−1.19406

1.13E-46

0.796 (0.5968523–1.06213)

0.124

hsa-miR-24

−1.09488

6.93E-31

0.9481 (0.7189929–1.250106)

0.706

hsa-miR-26a

−1.48288

8.51E-44

0.656 (0.5161167–0.8343482)

0.000469*

hsa-miR-29a

−1.20827

8.57E-23

0.829 (0.670324–1.024992)

0.0857

hsa-miR-615-3p

1.051951

6.30E-36

1.113 (0.8244393–1.502931)

0.486

hsa-miR-767-5p

1.179607

1.24E-13

1.0842 (0.8985411–1.308245)

0.387

hsa-miR-922

1.154044

7.59E-12

0.9802 (0.8252847–1.164265)

0.819

  1. Note: * Significant difference P < 0.05
  2.     logFC: log2 fold change; adj.P.Val: Benjamini-Hochberg-adjusted p-value