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Fig. 2 | Journal of Biomedical Science

Fig. 2

From: H19 knockdown suppresses proliferation and induces apoptosis by regulating miR-148b/WNT/β-catenin in ox-LDL -stimulated vascular smooth muscle cells

Fig. 2

Knockdown of H19 suppressed proliferation and induced apoptosis in ox-LDL-stimulated HA-VSMCs. HA-VSMCs transfected with si-con, si-H19#1 or si-H19#2 were treated with 50 μg/ml ox-LDL for 24 h, followed by the detection of H19 expression (a), proliferative capacity (b), clone formation ability (c), proliferation marker (PCNA and ki-67) expressions (d), apoptotic cell percentage (e), caspase-3 activity (f), and apoptosis-related protein (Bcl-2 and Bax) expressions (g). Data are presented as mean ± SEM (n = 3) of at three independent experiments.*P < 0.05

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Journal of Biomedical Science

ISSN: 1423-0127