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Fig. 2 | Journal of Biomedical Science

Fig. 2

From: Long non-coding RNA Gas5 regulates proliferation and apoptosis in HCS-2/8 cells and growth plate chondrocytes by controlling FGF1 expression via miR-21 regulation

Fig. 2

The effects of Gas5 and miR-21 in HCS-2/8 cells. a QRT-PCR assay was used to test the differential expression of Gas5, miR-21, FGF1 and caspase 9 in HCS-2/8 cells stably overexpressing Gas5. b The differential expression of Gas5, miR-21, FGF1 and caspase 9 in HCS-2/8 cells transfected with miR-21-inhibitor was determined by qRT-PCR assay. c Cell proliferation of HCS-2/8 gene function models assessed by MTT assays. d Cell survival rate assessed by MTT assays at 72 h. Data are presented as mean ± s.d., n = 3 or 5. *p < 0.05 or **p < 0.01 vs. control group

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