Fig. 6

FGF1 is a target of miR-21. a Different expression levels of GAS5 and FGF1 between DEX treatment and no treatment mouse chondrocytes. n = 6. b Putative binding sites of miR-21 within FGF1. c Luciferase activities of miR-21 and FGF1 were measured and normalised according to renilla luciferase activity. Data are presented as mean ± s.d., n = 3. *p < 0.05 or **p < 0.01 vs. control group. d FGF1 and cell proliferation and apoptosis genes network diagram