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Fig. 6 | Journal of Biomedical Science

Fig. 6

From: Flagellin-fused protein targeting M2e and HA2 induces potent humoral and T-cell responses and protects mice against various influenza viruses a subtypes

Fig. 6

Efficacy of immunization. Groups of 10 Balb/c mice were immunized with fusion proteins Flg-HA2–2-4M2ehs and FlgSh-HA2–2-4M2ehs. Two weeks post-second boost, mice were challenged with (a) 10LD50 A/Aichi/2/68 (H3N2) or (b) 10LD50 A/Shanghai/2/2013(H7N9)-PR8-IDCDC. Body weight (left) and survival rate (right) were monitored daily during 14 days. The P values (Montel-Cox test) between immunized and control groups are indicated

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