Table 2 Univariate analyses for progression-free and overall survival in lung adenocarcinoma
From: Prognostic value of localization of epidermal growth factor receptor in lung adenocarcinoma
Variable | High membranous EGFR | High nuclear EGFR | |||||||
|---|---|---|---|---|---|---|---|---|---|
Parameter | No | PFS | OS | PFS | OS | ||||
aHR (95%CI) | p | aHR (95%CI) | p | bHR (95%CI) | p | bHR (95%CI) | p | ||
All patients | 161 | 0.79 (0.56~ 1.13) | 0.198 | 0.71 (0.49~ 1.03) | 0.067 | 1.03 (0.73~ 1.46) | 0.865 | 0.81 (0.56~ 1.17) | 0.251 |
Older age (> 70 yr) | 84 | 0.64 (0.39~ 1.04) | 0.068 | 0.59 (0.36~ 0.97) | 0.038 | 0.81 (0.50~ 1.31) | 0.394 | 0.69 (0.40~ 1.10) | 0.101 |
Smokers | 58 | 0.62 (0.35~ 1.09) | 0.092 | 0.54 (0.30~ 0.99) | 0.046 | 0.61 (0.34~ 1.10) | 0.102 | 0.55 (0.30~ 0.99) | 0.043 |
Distant (metastasis) | 94 | 1.01 (0.66~ 1.56) | 0.954 | 0.83 (0.54~ 1.29) | 0.403 | 1.58 (1.01~ 2.45) | 0.043 | 1.10 (0.70~ 1.73) | 0.677 |
No brain metastasis | 114 | 0.63 (0.40~ 0.99) | 0.045 | 0.56 (0.34~ 0.91) | 0.019 | 1.01 (0.66~ 1.56) | 0.953 | 0.78 (0.49~ 1.25) | 0.297 |
Wildtype EGFR | 74 | 0.60 (0.35~ 1.03) | 0.059 | 0.64 (0.37~ 1.09) | 0.094 | 0.84 (0.50~ 1.41) | 0.506 | 0.74 (0.43~ 1.26) | 0.265 |