Table 1 The expression level of 11 DEGs
From: Identification of target genes in cardiomyopathy with fibrosis and cardiac remodeling
Gene | Control Mean ± SD(log) | DCM Mean ± SD(log) | Log2 (Fold change) | P-value |
|---|---|---|---|---|
collagen, type I, alpha 1(COL1A1) | 9.46 ± 0.56 | 11.04 ± 0.72 | 1.50 | 0.001 |
collagen, type I, alpha 2(COL1A2) | 8.73 ± 0.38 | 10.29 ± 1.00 | 1.50 | 0.004 |
cartilage oligomeric matrix protein(COMP) | 6.50 ± 0.24 | 7.86 ± 0.68 | 1.32 | 5.18 × 10-4 |
connective tissue growth factor(CTGF) | 8.51 ± 0.76 | 10.49 ± 0.52 | 1.93 | 1.50 × 10-4 |
periostin, osteoblast specific factor(POSTN) | 10.09 ± 0.68 | 11.38 ± 0.89 | 1.48 | 0.007 |
thrombospondin 2(THBS2) | 9.27 ± 0.25 | 10.39 ± 0.60 | 1.08 | 0.001 |
thrombospondin 4(THBS4) | 10.53 ± 0.78 | 10.76 ± 0.73 | 1.47 | 3.13 × 10-4 |
corin, serine peptidase(CORIN) | 8.57 ± 0.94 | 6.72 ± 1.15 | −1.86 | 0.008 |
c-fos induced growth factor (vascular endothelial growth factor D)(FIGF) | 8.78 ± 0.47 | 8.15 ± 0.53 | −1.23 | 0.035 |
ribosomal protein S4, Y-linked 1(RPS4Y1) | 8.10 ± 1.16 | 9.46 ± 1.90 | 1.38 | 0.039 |
proline/arginine-rich end leucine-rich repeat protein(PRELP) | 9.71 ± 0.44 | 10.81 ± 0.55 | 1.10 | 0.002 |