Table 2 Results of PASTAA analysis
From: Identification of target genes in cardiomyopathy with fibrosis and cardiac remodeling
Rank | Matrix | Transcription Factor | Association Score | P-Value |
|---|---|---|---|---|
a. TFs predicted to regulate up-regulated genes | ||||
1 | TATA_01 | Tbp | 4.51 | 2.22E-04 |
2 | TEF1_Q6 | Tef-1 | 4.1 | 5.01E-04 |
3 | TFIIA_Q6 | TfIIa-alpha/beta, TfIIa-gamma | 3.252 | 2.81E-03 |
4 | NFKAPPAB_01 | Rela | 2.876 | 6.51E-03 |
5 | NRL_HAND | N/A | 2.865 | 6.75E-03 |
6 | GFI1_01 | Gfi1 | 2.85 | 7.00E-03 |
7 | ALPHACP1_01 | N/A | 2.718 | 9.92E-03 |
8 | CREL_01 | C-rel | 2.587 | 1.15E-02 |
9 | TAL1BETAITF2_01 | Itf-2, Tal-1beta | 2.553 | 1.22E-02 |
10 | NFY_01 | N/A | 2.509 | 1.44E-02 |
b. TFs predicted to regulate down-regulated genes | ||||
1 | VMYB_01 | V-myb | 3.123 | 6.94E-04 |
2 | HNF4ALPHA_Q6 | Hnf-4, Hnf-4alpha | 3.043 | 9.08E-04 |
3 | MYB_Q3 | C-myb | 2.646 | 4.16E-03 |
4 | MYB_Q5_01 | B-myb, C-myb | 2.646 | 4.16E-03 |
5 | CDC5_01 | Cdc5 | 2.425 | 6.93E-03 |
6 | CEBP_Q2 | C/ebp, C/ebpalpha | 2.425 | 6.93E-03 |
7 | AP1_Q4_01 | Fosb, Fra-1 | 2.123 | 1.23E-02 |
8 | ZTA_Q2 | N/A | 2.123 | 1.23E-02 |
9 | AP1_Q2_01 | Fosb, Fra-1 | 2.044 | 1.23E-02 |
10 | COUP_01 | Coup-tf1, Hnf-4alpha1 | 2.044 | 1.23E-02 |