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Table 3 Correlation between p-Axl or p-TNS2 and various markers using pancreatic tissue arrays

From: AXL phosphorylates and up-regulates TNS2 and its implications in IRS-1-associated metabolism in cancer cells

  r p
pTensin2
 Glut4 - 0.037 0.082
 IRS-1 0.003 0.988
 Ki-67 0.106 0.556
 CD31 - 0.073 0.683
 E-cadherin 0.079 0.661
 N-cadherin 0.082 0.649
 Fibronectin 0.179 0.321
 Caspase3 0.263 0.139
 pAkt (nuclei) - 0.039 0.830
 pAkt (cytoplasm) 0.521 0.002*
 pErk (nuclei) 0.286 0.112
 pErk (cytoplasm) 0.018 0.919
pAxl
 Glut4 - 0.058 0.750
 IRS-1 0.273 0.125
 Ki-67 0.138 0.443
 CD31 0.209 0.244
 E-cadherin 0.037 0.836
 N-cadherin 0.437 0.011*
 Fibronectin 0.028 0.875
 Caspase3 0.087 0.631
 pAkt (nuclei) 0.423 0.014*
 pAkt (cytoplasm) 0.749 0.000*
 pErk (nuclei) 0.211 0.246
 pErk (cytoplasm) 0.286 0.107
  1. The correlations were evaluated using the Pearson correlation test
  2. Glut4 and IRS1 are involved in glycolysis; Ki-67, proliferation marker; CD31, angiogenesis marker; E-cadherin, epithelial marker; N-cadherin and fibronectin are mesenchymal markers; Caspase 3, apoptosis marker. Patient number = 33, *p < 0.05