Table 2 Technical details for establishing ESCC tumor xenograft models
From: Tumor xenograft animal models for esophageal squamous cell carcinoma
Tumor xenograft model | Technical details | References |
|---|---|---|
Subcutaneous | Starting material: human ESCC cell line | |
Injected cell number: 2 × 106 | ||
Mouse strain: nude, SCID, NOD/SCID | ||
Cell injection site: flank | ||
Orthotopic | Starting material: Human ESCC cell line | [23] |
Mouse strain: nude | ||
Tumor development site: cervical and abdominal esophagus | ||
Patient-derived | Starting material: Human ESCC tumor tissue | |
Mouse strain: NOD/SCID | ||
Tumor implantation method: subcutaneous |