Table 3 Uses of different tumor xenograft models for preclinical drug testing for ESCC
From: Tumor xenograft animal models for esophageal squamous cell carcinoma
Tumor xenograft models | Test compounds/drugs | References |
|---|---|---|
Subcutaneous | Temsirolimus | [14] |
Subcutaneous | YQ23 alone or combined with cisplatin or 5-fluorouracil | [16] |
Subcutaneous | Ginsenoside Rg3 alone or combined with paclitaxel and cisplatin | [15] |
Subcutaneous | Afatinib | [39] |
Orthotopic | Temsirolimus | [14] |
Patient-derived | Lapatinib alone and in combination with 5-fluorouracil or oxaliplatin | [25] |
Patient-derived | Cisplatin and 5-fluorouracil | [26] |
Patient-derived | Trastuzumab | [27] |