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Table 3 Uses of different tumor xenograft models for preclinical drug testing for ESCC

From: Tumor xenograft animal models for esophageal squamous cell carcinoma

Tumor xenograft models Test compounds/drugs References
Subcutaneous Temsirolimus [14]
Subcutaneous YQ23 alone or combined with cisplatin or 5-fluorouracil [16]
Subcutaneous Ginsenoside Rg3 alone or combined with paclitaxel and cisplatin [15]
Subcutaneous Afatinib [39]
Orthotopic Temsirolimus [14]
Patient-derived Lapatinib alone and in combination with 5-fluorouracil or oxaliplatin [25]
Patient-derived Cisplatin and 5-fluorouracil [26]
Patient-derived Trastuzumab [27]