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Table 4 Collections of patient-derived tumor xenograft models for ESCC

From: Tumor xenograft animal models for esophageal squamous cell carcinoma

Number of established models Characterized deregulations References
37 EGFR, K-ras, B-raf and PIK3CA mutation HER2 expression [26]
25 HER2 expression and amplification [27]
5 EGFR, K-ras, B-raf and PIK3CA mutation HER2 expression and amplification [27]
  1. Abbreviations used: EGFR epidermal growth factor receptor, HER2 human epidermal growth factor receptor 2 PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha