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Table 4 Collections of patient-derived tumor xenograft models for ESCC

From: Tumor xenograft animal models for esophageal squamous cell carcinoma

Number of established models

Characterized deregulations

References

37

EGFR, K-ras, B-raf and PIK3CA mutation HER2 expression

[26]

25

HER2 expression and amplification

[27]

5

EGFR, K-ras, B-raf and PIK3CA mutation HER2 expression and amplification

[27]

  1. Abbreviations used: EGFR epidermal growth factor receptor, HER2 human epidermal growth factor receptor 2 PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
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Journal of Biomedical Science

ISSN: 1423-0127