From: The TRAX, DISC1, and GSK3 complex in mental disorders and therapeutic interventions
Pathway | Binding partner | Full name | Interaction with TRAX | Interaction with DISC1 |
---|---|---|---|---|
cAMP/PKA | A2A adenosine receptor | + [132] | Nd | |
Akap9 [168] | A-Kinase Anchoring Protein 9 | + [168] | ||
ATF4 | Activating Transcription Factor 4 | nd | ||
ATF5 | Activating Transcription Factor 5 | nd | ||
ATF7IP | Activating Transcription Factor 7 | nd | + [194] | |
D2R | Dopamine D2 receptor | nd | + [146] | |
PDE4B | Phosphodiesterase 4B | nd | ||
PDE4D | Phosphodiesterase 4D | nd | ||
Wnt signaling | GSK3β [5] | Glycogen Synthase Kinase 3 β | + [5] | |
β-catenin | Catenin β-1 | nd | ||
DIXDC1 | DIX Domain Containing 1 | nd | ||
TNIK | TRAF2 And NCK Interacting Kinase | nd | ||
WNT3A | Wnt Family Member 3A | nd | + [194] | |
Intracellular Transport | Dynactin | Dynactin | nd | + [207] |
FEZ1 | Fasciculation And Elongation Protein Zeta 1 | nd | ||
HZF | Haematopoetic zinc finger | nd | + [12] | |
KIF1B | Kinesin Family Member 1B | nd | + [12] | |
KIF2A | Kinesin Family Member 2A | nd | ||
KIF5A | Kinesin Family Member 5A | nd | ||
Miro1/2 | Mitochondrial Rho GTPase 1/2 | nd | ||
SNPH | Syntaphilin | nd | + [10] | |
TRAK1/2 | Trafficking kinesin protein-1/2 | nd | + [9] | |
Translin | Tanslin | + [211] | nd | |
DNA repair | ATM | ataxia-telangiectasia mutated | + [137] | nd |
C1D | nuclear matrix protein C1D | + [136] | nd | |
Rad21 | Double-strand-break repair protein rad21 homolog | Nd |