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Table 4 The comparison of serum levels of gastrin, PG I and II among NUD subjects with the different status of HtrA-L171 & CagL-Y58/E59 of H. pylori infection

From: H. pylori isolates with amino acid sequence polymorphisms as presence of both HtrA-L171 & CagL-Y58/E59 increase the risk of gastric cancer

Parameters, mean (SD) HtrA-L171 & CagL-Y58/E59 status P value
Both absence (n = 11) HtrA-171 L alone (n = 7) CagL-Y58/E59 alone (n = 6) Both presence (n = 5)
Gastrin (pg/ml) 34.0 (26.9) 96.6 (36.8) 60.8 (48.0) 54.6 (20.7) 0.003a
PG I (ng/ml) 105.3 (59.2) 112.3 (27.7) 116.8 (29.0) 99.6 (26.1) NS
PG II (ng/ml) 12.2 (6.1) 11.5 (5.0) 17.4 (8.6) 11.7 (3.9) NS
PG I/II 9.0 (3.2) 10.6 (3.2) 7.4 (1.8) 9.4 (4.2) NS
  1. Abbreviations: PG pepsinogen. Statistical analysis was performed by t test. a indicated significance with P < 0.05 of such parameter between both absence of HtrA-L171 & CagL-Y58/E59 and HtrA-L171 only H. pylori infection. NS: no significant difference