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Table 4 The comparison of serum levels of gastrin, PG I and II among NUD subjects with the different status of HtrA-L171 & CagL-Y58/E59 of H. pylori infection

From: H. pylori isolates with amino acid sequence polymorphisms as presence of both HtrA-L171 & CagL-Y58/E59 increase the risk of gastric cancer

Parameters, mean (SD)

HtrA-L171 & CagL-Y58/E59 status

P value

Both absence (n = 11)

HtrA-171 L alone (n = 7)

CagL-Y58/E59 alone (n = 6)

Both presence (n = 5)

Gastrin (pg/ml)

34.0 (26.9)

96.6 (36.8)

60.8 (48.0)

54.6 (20.7)

0.003a

PG I (ng/ml)

105.3 (59.2)

112.3 (27.7)

116.8 (29.0)

99.6 (26.1)

NS

PG II (ng/ml)

12.2 (6.1)

11.5 (5.0)

17.4 (8.6)

11.7 (3.9)

NS

PG I/II

9.0 (3.2)

10.6 (3.2)

7.4 (1.8)

9.4 (4.2)

NS

  1. Abbreviations: PG pepsinogen. Statistical analysis was performed by t test. a indicated significance with P < 0.05 of such parameter between both absence of HtrA-L171 & CagL-Y58/E59 and HtrA-L171 only H. pylori infection. NS: no significant difference
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Journal of Biomedical Science

ISSN: 1423-0127