Fig. 2
From: The emerging roles and functions of circular RNAs and their generation
CircRNA regulates cell proliferation. CircRNA regulates cell proliferation through multiple factors, including (a) FGF2 and EGFR in MAPK/ERK pathway, (b) PI3K in PI3K/AKT pathway, (c) WNT2, FZD4, ITCH, CBL, APC2, and β-catenin in WNT/β -catenin pathway, and (d) CDK6, E2F3, PTEN, P21 and CDK2 that regulate cell cycle. CircRNAs promote or inhibit cells proliferation are labeled by black and red, respectively