Fig. 5
From: Host immune response to anti-cancer camptothecin conjugated cyclodextrin-based polymers
IT-101 attenuated the brain tumor growth at early stage of tumorigenesis. (a) (b) 2-month-old F1B transgenic mice were treated with IT-101 and PBS respectively by intravenous injection, one dose with booster doses. After two months ago, the tumor size was measured using histopathological data. (c) (d) 4-month-old F1B transgenic mice were treated with IT-101 and PBS respectively by Intraperitoneal injection, one dose with booster doses. After two months ago, the tumor size was measured using histopathological data. Mouse number per group, 3–5 mice. The results are presented as the mean ± SD. *p < 0.05; **p < 0.005