From: Development and clinical applications of cancer immunotherapy against PD-1 signaling pathway
 | Pembrolizumab | Nivolumab | Atezolizumab |
---|---|---|---|
Breast cancer, triple negative, first-line | – | – | IC ≥ 1% |
Cervical cancer, second-line | CPS ≥ 1 | – | – |
Colorectal cancer, second-line | MSI-high | MSI-high | – |
Esophageal cancer, second-line | CPS ≥10 | – | – |
Gastric cancer, second-line | CPS ≥1 | – | – |
Head and neck cancer, first-line | CPS ≥1 | – | – |
Non-small cell lung cancer, first-line | CPS ≥1 | – | – |
Urothelial carcinoma, first-line | CPS ≥10 | – | IC ≥ 5% |
Solid tumor, second-line | MSI-high | – | – |