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Fig. 1 | Journal of Biomedical Science

Fig. 1

From: Mode of action of granulocyte-colony stimulating factor (G-CSF) as a novel therapy for stroke in a mouse model

Fig. 1

Effect of G-CSF on expression of G-CSFR, G-CSF and P-Akt proteins. a G-CSFR proteins levels in the frontal (F (2, 8) = 7.519, p = 0.014) and middle (F (2, 9) = 26.45, p = 0.0002) region of the brain. b G-CSF proteins levels in the frontal (F (2, 20) = 18.58, p < 0.0001) and middle (F (2, 14) = 6.319, p = 0.0111) region of the brain. c Akt proteins levels in the frontal (F (2, 5) = 12.19, p = 0.0120) and middle (F (2, 11) = 1.460, p = 0.2740) region of the brain. P-Akt levels in frontal (F (2, 14) = 7.215, p = 0.0070 and middle (F (2, 11) = 9.246, p = 0.0044) region of the brain. d P-Akt/Akt ratio expression in the frontal (F (2, 7) = 12.5, p = 0.0048) and middle (F (2, 11) = 19.83, p = 0.0002) region of the brain. e TTC representation of infarcted regions. White areas indicative of . Protein levels were normalized by the corresponding GAPDH and related total protein expressions. The values are the percentage of the corresponding relative intensity of the control (Sham). Representative western blots are presented with cropped blot panels showing target protein signals and control (GAPDH) protein signals in separate panels derived from the same gel. Graphs show mean ± SEM. * and # significant compared to sham & vehicle treated group, respectively by ANOVA and Tukey post hoc tests (n = 5, p < 0.05)

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