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Table 1 Multiparametric logistic regression analysis to express the relationship of classification by the combined BPA/UPA proteomic test with demographic and clinical variables for the prediction of overall survival within the first year of clinical follow-up after proteomic analysis. The regression coefficient in the table expresses the amount of change in the logit function related to one unit change in the predictor

From: Bile and urine peptide marker profiles: access keys to molecular pathways and biological processes in cholangiocarcinoma

Independent variableRegression coefficientStandard errorSignificance level POdds ratio (95% CI)
BPA/UPA match0.51700.22400.021.68 (1.08–2.60)
Age (year)0.00560.03510.871.01 (0.94–1.08)
Gender (female = 0, male = 1)−0.18111.13470.870.83 (0.09–7.71)
Alkaline phosphatase (U/L)−0.01170.00650.070.99 (0.98–1.00)
γ-Glutamyltransferase (U/L)0.00170.00160.311.00 (1.00–1.00)
Bilirubin (μmol/L)−0.00880.00890.330.99 (0.97–1.01)
Leucocyte count (N)0.000260.000170.121.00 (1.00–1.00)
C-reactive protein (mg/L)0.01340.01030.201.01 (0.99–1.03)
Alanine aminotransferase (U/L)−0.00710.01590.660.99 (0.96–1.02)
Aspartate aminotransferase (U/L)0.02020.02490.421.02 (0.97–1.07)
Carbohydrate antigen 19–9 (kU/L)0.0000460.0000920.621.00 (1.00–1.00)