Table 2 Antimicrobial susceptibility profiles of the K. pneumoniae and E. coli strains used in this study
Strain | MIC (mg/L) (antimicrobial susceptibility category)a, b | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
IMI | MRP | CTX | CAZ | AMP | GEN | AMK | CIP | TET | SXT | P/T | CL | |
Donor (K. pneumoniae M5) | > 64 (R) | > 64 (R) | > 128 (R) | > 64 (R) | > 64 (R) | > 64 (R) | > 128 (R) | > 64 (R) | 8 (I) | > 32/608 (R) | > 256/4 (R) | 0.5 (S) |
Recipient (E. coli DH5α) | 0.125 (S) | 0.06 (S) | 0.125 (S) | 0.5 (S) | 4 (S) | 1 (S) | 4 (S) | 0.06 (S) | 0.5 (S) | 0.25/4.75 (S) | 4/4 (S) | 0.06 (S) |
DH5α::pM5_NDM | 4 (R) | 0.5 (S) | > 128 (R) | > 64 (R) | > 64 (R) | > 64 (R) | > 128 (R) | 0.06 (S) | 0.5 (S) | > 32/608 (R) | > 256/4 (R) | 0.125 (S) |
DH5α::pM5_OXA | 1 (S) | 0.25 (S) | 4 (S) | 0.5 (S) | > 64 (R) | 4 (S) | 16 (S) | 0.06 (S) | 0.5 (S) | 2/38 (S) | > 256/4 (R) | 0.06 (S) |
DH5α::pM5_NDM +pM5_OXA | 4 (R) | 1 (S) | > 128 (R) | > 64 (R) | > 64 (R) | > 64 (R) | > 128 (R) | 0.06 (S) | 0.5 (S) | > 32/608 (R) | > 256/4 (R) | 0.06 (S) |