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Table 1 MicroRNAs involve in hypoxia-mediated human diseases

From: Pathophysiological implications of hypoxia in human diseases

MicroRNA(s)Change in expressionRegulatory gene(s)Disease(s)
miR-18aUpBDNFMyocardial infarction
miR-21UpPDCD4
Spry1
Heart failure
Heart failure
miR-22
miR-34a
UpSIRT1Hypertrophy
miR-98DownDAPK1Ischemia/reperfusion
miR-134UpNOS3Ischemia/reperfusion
miR-135a
miR-203
Down
Down
PTP1BIschemia/reperfusion
Myocardial infarction
miR-144DownFOXO1Ischemia/reperfusion
miR-146a-5pUpXIAPIntermittent hypoxia
miR-210UpEFNA3
PTP1B
HIF-3α
Vascular remodeling
miR-327UpCRDIschemia/reperfusion
miR-340-5pDownAct1Ischemia/reperfusion
miR-374a-5pDownMAPK6Ischemia/reperfusion
miR-429DownMO25Ischemia/reperfusion
miR-1192DownCASP3Myocardial infarction