Table 1 MicroRNAs involve in hypoxia-mediated human diseases
From: Pathophysiological implications of hypoxia in human diseases
MicroRNA(s) | Change in expression | Regulatory gene(s) | Disease(s) |
|---|---|---|---|
miR-18a | Up | BDNF | Myocardial infarction |
miR-21 | Up | PDCD4 Spry1 | Heart failure Heart failure |
miR-22 miR-34a | Up | SIRT1 | Hypertrophy |
miR-98 | Down | DAPK1 | Ischemia/reperfusion |
miR-134 | Up | NOS3 | Ischemia/reperfusion |
miR-135a miR-203 | Down Down | PTP1B | Ischemia/reperfusion Myocardial infarction |
miR-144 | Down | FOXO1 | Ischemia/reperfusion |
miR-146a-5p | Up | XIAP | Intermittent hypoxia |
miR-210 | Up | EFNA3 PTP1B HIF-3α | Vascular remodeling |
miR-327 | Up | CRD | Ischemia/reperfusion |
miR-340-5p | Down | Act1 | Ischemia/reperfusion |
miR-374a-5p | Down | MAPK6 | Ischemia/reperfusion |
miR-429 | Down | MO25 | Ischemia/reperfusion |
miR-1192 | Down | CASP3 | Myocardial infarction |