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Table 2 Non-singleton mutations detected across the sampled SARS-CoV-2 genomes

From: The origin and underlying driving forces of the SARS-CoV-2 outbreak

 

Genome position

Gene

RaTG13

Pangolin_2017

Pangolin_2019

Major allele

Minor allele

amount of change

 

Nonsynonymous

     

I

II

 

 A

614

orf1ab

G

G

G

G

A

2

 

H116Q

 B

1190

orf1ab

C

C

C

C

T

3

 

P308S

 C

5084

orf1ab

A

A

A

A

G

2

 

A1606T

 D

9438

orf1ab

C

C

C

C

T

3

 

T3058I

 E

11,083

orf1ab

G

T

G

G

T

9

 

L3606F

 F

18,488

orf1ab

T

T

T

T

C

2

 

I6074V

 G

21,707

S

C

C

N/A

C

T

5

 

H48Y

 H

22,661

S

G

G

G

G

T

5

 

V366F

 I

26,144

orf3

G

G

G

G

T

18

 

G251V

 J

27,147

M

G

G

G

G

C

2

 

I208T

 K

28,077

orf8

G

G

G

G

C

4

 

V61L

 L

28,144

orf8

C

C

C

T

C

99

38

L84S

 M

28,854

N

C

C

C

C

T

5

 

S194L

 N

28,878

N

G

G

G

G

A

6

 

S202N

 O

29,019

N

A

A

A

A

T

2

 

D249H

 P

29,303

N

C

C

C

C

T

2

 

K343I

Synonymous

 α

2662

orf1ab

C

T

T

C

T

3

 

C2397T

 β

8782

orf1ab

T

T

T

C

T

100

37

C8517T

 γ

10,138

orf1ab

T

T

T

C

T

134

3

C9873T

 δ

15,324

orf1ab

C

C

C

C

T

2

 

C15059T

 ϵ

17,373

orf1ab

T

C

T

C

T

132

5

C17108T

 ζ

18,060

orf1ab

T

T

A

C

T

131

6

C17795T

 η

18,603

orf1ab

T

T

C

T

A

2

 

T18338C

 θ

23,569

S

A

C

A

T

C

2

 

T2007C

 ι

23,605

S

N/A

N/A

N/A

T

G

2

 

T2043G

 κ

24,034

S

T

C

C

C

T

131

6

C2472T

 λ

24,325

S

A

A

A

A

G

2

 

A2763G

 μ

26,729

M

T

T

T

T

C

4

 

T207C

 ν

29,095

N

T

T

T

C

T

125

12

C822T

  1. I: Number of changes was inferred by outgroup comparison only
  2. II: Number of changes was cross-referenced with the haplotype network of SARS-CoV-2;only numbers different from method I were shown
  3. E: envelope; M: matrix; N: nucleocapsid; S: spike
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Journal of Biomedical Science

ISSN: 1423-0127