Table 3 Comparison of dN, dS, and dN/dS estimates in the coding regions of SARS-CoV-2 without singleton between two episodes
From: The origin and underlying driving forces of the SARS-CoV-2 outbreak
Gene | Episode I (N = 57) (2019/12/24–2020/1/21) | Episode II (N = 79) (2020/1/22–2020/2/23) | Episode I + II (2019/12/24–2020/2/23) | |||
|---|---|---|---|---|---|---|
|  | dN ×  104 | dS × 104 | dN × 104 | dS × 104 | dN X 104 | dS X 104 |
dN/dS | dN/dS | dN/dS | ||||
All | 0.34 | 1.70 | 0.78 | 1.98 | 0.61 | 1.87 |
0.20 | 0.39 | 0.32 | ||||
orf1a | 0.10 | 1.46 | 0.37 | 2.15 | 0.26 | 1.85 |
0.07 | 0.17 | 0.14 | ||||
orf1b | 0.06 | 0.81 | 0.08 | 1.60 | 0.07 | 1.29 |
0.07 | 0.05 | 0.05 | ||||
spike | 0.23 | 2.49 | 0.64 | 1.82 | 0.48 | 2.10 |
0.09 | 0.35 | 0.23 | ||||
orf3 | 0.00 | 0.00 | 5.30 | (1.98)* | 3.42 | (1.87)* |
0.00 | 2.68 | 1.83 | ||||
envelope | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 |
0.00 | 0.00 | 0.00 | ||||
matrix | 0.00 | 4.60 | 0.97 | 3.37 | 0.57 | 3.86 |
0.00 | 0.29 | 0.15 | ||||
orf6 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 |
0.00 | 0.00 | 0.00 | ||||
orf7 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 |
0.00 | 0.00 | 0.00 | ||||
orf8 | 16.26 | (1.70)* | 15.84 | (1.98)* | 15.90 | (1.87)* |
9.57 | 8.02 | 8.51 | ||||
nucleocapsid | 1.16 | 7.31 | 2.98 | 4.26 | 2.25 | 5.61 |
0.16 | 0.70 | 0.40 | ||||