Fig. 6
From: Constructing conjugate vaccine against Salmonella Typhimurium using lipid-A free lipopolysaccharide
Immunization scheme (a) and Kaplan-Meier survival curves (b&c) for the challenge experiments of mice immunized with PS–protein vaccines. Each group was conducted with 9 or 10 BALB/c mice, which were s.c. administered with the vaccine at a dosage of 2.5 μg according to the immunization scheme. The immunized mice were then orally challenged with 1 × 106 CFU LD50 (b) or lethal dose (c) of S. Typhimurium SL1344 bacteria. The data were derived from two independent experiments. PS was unfractionated LFPS prepared from the LPS of S. Typhimurium ATCC7823. The log-rank test was used to compare the survival of mice in the immunized and control groups