Fig. 4
From: Dissecting the conformation of glycans and their interactions with proteins
Molecular dynamics simulation revealed that the conformation of glycan regulated the binding between SPARC and collagen. Comparison of the conformation of the biantennary or bisecting N-glycans of SPARC from 293 T-WT cells (a), 293 T-Fut8KO cells (b), and platelets (c) by molecular dynamics simulation (lower panels). The upper panels show schematic drawings of the conformational changes of the N-glycans of SPARC