Fig. 1
From: Autophagosome formation in relation to the endoplasmic reticulum
Schematic representation of the endoplasmic reticulum (ER) and the ER subdomain. The ER network is composed of tubules and sheet-like structures that are formed by the ER-shaping proteins, of which reticulon (red) creates the curvature of the ER membrane. CLIMP-63 (orange), which is a single spanning ER membrane protein, forms an oligomer into the ER luminal space to maintain the ER sheet structure. Atlastin (blue) localizes on the three-way junction of the ER network to create an interconnection of the ER tubules. The inset region shows the ER tubular matrices within the ER sheet structures. DFCP1 (green) localizes and forms the omegasome structures on the ER subdomain