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Fig. 5 | Journal of Biomedical Science

Fig. 5

From: CircNOL10 suppresses breast cancer progression by sponging miR-767-5p to regulate SOCS2/JAK/STAT signaling

Fig. 5

CircNOL10-mediated suppressive effects on BC cell malignant behaviors are reversed by miR-767-5p up-regulation. ad BT-549 and MDA-MB-231 cells were transfected with miR-NC, miR-767-5p, miR-NC + circNOL10 or miR-767-5p + circNOL10. a Plate clonality assays were used to monitor the colony forming ability. b, c Transwell assays were performed to examine cell migration and invasion. d Western blot assays were applied to determine the protein expression of EMT-related genes including E-cadherin, N-cadherin and vimentin.*P < 0.05, **P < 0.01, ***P < 0.001

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