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Fig. 7 | Journal of Biomedical Science

Fig. 7

From: CircNOL10 suppresses breast cancer progression by sponging miR-767-5p to regulate SOCS2/JAK/STAT signaling

Fig. 7

SOCS2 overexpression inhibits BC cell proliferation, migration, invasion and EMT. a SOCS2-overexpressing plasmid (SOCS2) was transfected into BT-549 and MDA-MB-231 cells, followed by western blot analysis of SOCS2 protein level. b CCK-8 assays were used to determine the effect of SOCS2 on cell viability. c Colony forming assays were performed in BT-549 and MDA-MB-231 cells with SOCS2 overexpression. d, e Transwell assays were applied to evaluate the migration and invasion abilities of SOCS2-overexpressing cells. f Western blot analysis of E-cadherin, N-cadherin and vimentin expressions in SOCS2-transfected cells. **P < 0.01, ***P < 0.001

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Journal of Biomedical Science

ISSN: 1423-0127