Fig. 7
From: FKBP10 promotes proliferation of glioma cells via activating AKT-CREB-PCNA axis
Expression level of FKBP10 related molecules in subcutaneous xenografts and glioma tissues. a Representative immunostaining images of FKBP10, p-AKT (Ser473), p-CREB (Ser133) and PCNA in FKBP10 parental and shRNA subcutaneous xenografts. Scale bar = 50 μm. b Representative immunostaining images of Hsp47, p-CREB (Ser133) and PCNA in grade 2, 3 and 4 gliomas. Scale bar = 25 μm. c Correlation analysis between FKBP10 expression and Hsp47 expression. d, e Expression of p-CREB (Ser133) and PCNA in high and low FKBP10 gliomas. f–h Survival analysis of Hsp47, p-CREB (Ser133) and PCNA overexpression in grade 4 glioma. ***P < 0.001