Fig. 4
From: Design, synthesis, and preliminary evaluation of a potential synthetic opioid rescue agent
Dose-dependence of antagonist effects of compound 29 (0.01–0.1 mg/kg, IP), administered 30 min before oxycodone (5.6 mg/kg), in the thermal antinociception assay. X-axis: Time in minutes after oxycodone administration. Y-axis: %Maximum possible effect (%MPE)