Fig. 8

Behavioral activity in the automated cages during alcohol drinking conditioning and extinction tests after viral overexpression of GDNF and BDNF. A Schematic representation of the experimental timeline. B Number of visits in the corner. C Number of nosepokes in conditioned CS + side. D Number of licks in CS + side. E The ethanol dose that mice consumed during alcohol drinking conditioning was estimated as g/kg/24 h. F Spread of AAV-GFP viral vector in the nucleus accumbens is demonstrated by GFP immunohistochemistry. G Number of visits to the corner on WD1 and WD10. H Number of nosepokes in CS + and CS− sides on WD1 and WD10. I A number of licks in CS + and CS− sides on WD1 and WD10. *p < 0.05, ***p < 0.001. All means are presented with their standard errors (± SEM)