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Fig. 1 | Journal of Biomedical Science

Fig. 1

From: Reprogramming of arachidonate metabolism confers temozolomide resistance to glioblastoma through enhancing mitochondrial activity in fatty acid oxidation

Fig. 1

Regulation of phospholipid and AA metabolism by Sp1. a Sp1-regulated metabolic genes. After Sp1 knockdown by siRNA, U87MG cell RNA was collected and subjected to RNA-Seq. b AA-related metabolite alteration determined via UHPLC-QTOF-MS. U87MG and U87MG-Sp1 cKO cells were subjected to mass spectrometry-based metabolomics analysis. The alteration of metabolite levels was illustrated by performing two-tailed unpaired Student’s t test. The chemical structures were obtained from PubChem, National Library of Medicine. The complete definitions of the different abbreviations are provided in Additional file 1: Table S5

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Journal of Biomedical Science

ISSN: 1423-0127