Fig. 6From: The effects of SARS-CoV-2 infection on modulating innate immunity and strategies of combating inflammatory response for COVID-19 therapyA positive feedback loop between infected macrophages and T cells. The infected alveolar macrophages by SARS-CoV-2 activate T cells (CD4+ and CD8+), which helps the release of interferon-γ. This facilitates tissue-resident alveolar macrophages to release cytokines, and further encourages the activation of T cells and form a positive loop. (Created with BioRender.com.)Back to article page