Fig. 5

A Temporal changes in mean arterial pressure (MAP), heart rate (HR) or power density of the low-frequency (BLF) component of systolic blood pressure spectrum measured by radiotelemetry in mice before (0 h) and 2, 12 or 24 h after administration of AOM (100 μg/g, i.p.). Values are mean ± SEM, n = 6 animals per experimental group. *p < 0.05 vs. 0 h group in the post hoc Dunnett multiple-range test. B Changes in MAP, HR or BLF power 24 h after administration of AOM (100 μg/g, i.p.) in mice that received pretreatment by i.c.v. infusion of mouse IgG (0.004 μg/h) or VEGF Ab (0.004 μg/h). Values are mean ± SEM, n = 7 animals per experimental group. *p < 0.05 versus IgG group in the Student’s t-test