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Fig. 4 | Journal of Biomedical Science

Fig. 4

From: Recent advances in conventional and unconventional vesicular secretion pathways in the tumor microenvironment

Fig. 4

Intracellular trafficking routes in the biogenesis of exosomes and ectosomes. During the biogenesis of exosomes, Rab GTPases play an important role in regulation of multiple intracellular trafficking steps including cargo collection into MVBs, transportation of MVBs toward plasma membrane and membrane fusion for ILVs release. Besides, the Rab family is also involved in ectosome formation

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Journal of Biomedical Science

ISSN: 1423-0127