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Table 3 Distribution of VF genes in E. coli phylogenetic group B2 isolates from children by ST131 status

From: Possible step-up in prevalence for Escherichia coli ST131 from fecal to clinical isolates: inferred virulence potential comparative studies within phylogenetic group B2

VF genesb

Number (%) of isolates with trait by source and ST131 status

P value by isolate source (vs. ST131)a

Fecal (n = 106)

Clinical (n = 237)

ST131 (n = 14)

Non-ST131 (n = 92)

ST131 (n = 32)

Non-ST131 (n = 205)

Fecal

cClinical

afa/draBC

2 (13)

3 (3)

8 (25)

27 (13)

0.03

0.002

bmaE

0 (0)

0 (0)

1 (3)

0 (0)

NS

0.03

sfaS

3 (21)

14 (15)

6 (19)

27 (13)

0.01

0.045

fimH

14 (100)

91 (99)

32 (100)

201(98)

NS

NS

focG

14 (100)

46 (50)

32 (100)

115 (56)

< 0.001

< 0.001

papGI

0 (0)

1 (1)

0 (0)

0 (0)

NS

NS

papGII

2 (13)

9 (10)

7 (22)

23 (11)

NS

< 0.001

papGIII

3 (21)

14 (15)

13 (41)

29 (14)

0.01

< 0.001

papAH

4 (29)

19 (21)

13 (41)

27 (13)

0.043

< 0.001

papC

4 (29)

17 (18)

15 (47)

37 (18)

0.003

< 0.001

papEF

5 (36)

17 (18)

16 (50)

52 (25)

0.004

< 0.001

gafD

0 (0)

0 (0)

1 (3)

0 (0)

NS

NS

cnf1

3 (21)

14 (15)

10 (31)

44 (21)

0.01

0.01

hlyA

3 (21)

8 (9)

10 (31)

37 (18)

0.009

0.003

iutA

14 (100)

63 (68)

32 (100)

156 (76)

< 0.001

< 0.001

fyuA

10 (71)

30 (33)

32 (100)

132 (64)

< 0.001

< 0.001

iroN

8 (57)

30 (33)

20 (63)

78 (38)

< 0.001

< 0.001

kpsMTII

3 (21)

5 (5)

32 (100)

0 (0)

< 0.001

< 0.001

kpsMTIII

0 (0)

0 (0)

1 (3)

0 (0)

NS

NS

traT

14 (100)

63 (68)

32 (100)

152 (74)

< 0.001

< 0.001

ompT

14 (100)

62 (67)

32 (100)

150 (73)

< 0.001

< 0.001

Usp

14 (100)

59 (64)

32 (100)

162 (79)

< 0.001

< 0.001

  1. aP values are shown where P < 0.05, calculated by Fisher’s exact test. NS, non-significant
  2. bThe 22 virulence factors analyzed were; papA, P fimbriae structural subunit; papC, P fimbriae assembly; papEF, fimbriae tip pilins; papG, P fimbriae adhesin (and alleles I, II and III); sfaS, S fimbriae; focG, F1C fimbriae; afa/draBC, Afimbrial adhesin (Dr-binding adhesin); fimH, type 1 fimbriae; hlyA, hemolysin; cnf1, cytotoxic necrotizing factor type1; fyuA, ferric yersiniabactin receptor; iutA, aerobactin receptor; iroN, catecholate siderophore receptor; kpsMTII group 2 capsule (with K1 and K2 variants); kpsMTIII, group 3 capsule; traT, serum-resistance associated; ompT, outer membrane protein T (protease); bmaE, M fimbriae; gafD, (G) fimbriae
  3. cClinical, cystitis and pyelonephritis isolates