Fig. 5
![Fig. 5](http://media.springernature.com/full/springer-static/image/art%3A10.1186%2Fs12929-022-00867-2/MediaObjects/12929_2022_867_Fig5_HTML.png)
Risk score is correlating with immunosuppressive tumor microenvironment in COAD patients. A Hierarchical cluster and heatmap of the enrichment scores of the various gene sets related to immune functions on the COAD patients (n = 334). B Boxplot indicating the sum of the immune enrichment scores (SIES) in cluster1 and clsuter2. p-value is calculated by unpaired two tailed t test. C Boxplot indicating the risk score of COAD patients in cluster1 and cluster 2 (n = 313). p-value is calculated by unpaired two tailed t test. D Boxplot indicating the SIES in patients of low- and high- risk (according to the risk score stratification). p-value is calculated by unpaired two tailed t test. E Dot heatmap of the Pearson correlation between risk score and enrichment score of the various gene sets related to immune functions. Dot size indicate the correlation extent