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Table 1 Deregulated putative eRNAs annotated to photoreceptor specific genes of SCA7 mouse retina

From: Polyglutamine-expanded ATXN7 alters a specific epigenetic signature underlying photoreceptor identity gene expression in SCA7 mouse retinopathy

Putative mouse eRNA

SCA7/WT expression in mouse retina

Annotated PR specific gene

eRNA length [nt]

Cluster 10

Putative eRNA

mRNA

log2[FC]

adj. p value

log2[FC]

adj. p value

Aipl1

10,702

Yes

− 0,09

7,69E-01

− 0,16

6,14E-02

Arl4d

16,798

Yes

− 0,60

7,93E-04

− 0,78

5,27E-47

Cnga1

5168

Yes

− 0,58

2,54E-02

− 0,97

2,89E-38

Cngb1

7060

Yes

− 0,64

2,25E-03

− 0,62

1,22E-11

Crb1

5376

–

− 0,61

2,68E-02

− 0,26

2,00E-03

Crb2

7515

Yes

− 0,75

1,73E-03

− 0,32

6,54E-03

Fam161a

11,761

Yes

− 0,58

4,94E-03

− 0,59

3,67E-10

Gnat1

25,096

Yes

− 1,97

1,84E-88

− 1,75

2,79E-67

Gnb1

8377

Yes

− 1,14

1,04E-05

− 1,31

7,31E-48

Gngt1

7490

–

− 0,38

1,38E-01

− 1,06

3,50E-19

Grk1

12,836

Yes

− 1,54

5,72E-22

− 0,93

1,14E-34

Guca1b

9997

Yes

− 2,76

5,92E-36

− 1,64

1,49E-56

Heg1

10,544

Yes

− 1,02

4,92E-05

0,66

7,32E-09

Pcbp4

5495

–

− 1,12

1,98E-16

− 0,51

1,38E-06

Pde6b

12,407

Yes

− 0,71

5,52E-06

− 1,16

2,46E-46

Plpp2

7475

Yes

− 1,59

4,06E-06

− 1,13

3,60E-21

Prph2

20,958

Yes

− 1,61

9,62E-35

− 1,44

3,24E-74

Rbp3

9662

Yes

− 0,13

6,09E-01

− 0,27

2,02E-02

Rho

19,220

Yes

− 1,49

4,58E-25

− 2,10

3,02E-99

Rp1l1

6869

Yes

− 1,20

1,27E-13

− 0,41

3,97E-05

Rpgrip1

14,808

–

0,01

9,74E-01

− 0,52

3,49E-07

Sag

9708

Yes

− 1,44

7,13E-08

− 1,21

2,45E-29

Slc24a1

10,736

Yes

− 0,98

8,89E-07

− 0,65

2,62E-10

Unc119

10,843

Yes

− 1,08

1,51E-11

− 1,12

7,07E-30

  1. Bold are downregulated photoreceptor (PR) specific genes annotated to downregulated putative eRNAs; FC: fold change