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Fig. 1 | Journal of Biomedical Science

Fig. 1

From: LSD1: an emerging face in altering the tumor microenvironment and enhancing immune checkpoint therapy

Fig. 1

Structural features of the various parts of LSD1. The crystal structure of the protein was obtained from RCSB PDB (ID:2HKO). N-flexible region and SWIRM domain mostly function as interactions with other proteins, whilst AOL-N and TOWER domain operate demethylase activity. The AOL-C domain recognizes specific substrates to demethylase. N-flexible region and C domain have not shown in the crystal structure

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