Fig. 1From: LSD1: an emerging face in altering the tumor microenvironment and enhancing immune checkpoint therapyStructural features of the various parts of LSD1. The crystal structure of the protein was obtained from RCSB PDB (ID:2HKO). N-flexible region and SWIRM domain mostly function as interactions with other proteins, whilst AOL-N and TOWER domain operate demethylase activity. The AOL-C domain recognizes specific substrates to demethylase. N-flexible region and C domain have not shown in the crystal structureBack to article page