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Table 3 Ongoing phase 2 anti-amyloid therapy trials

From: Clinical trials of new drugs for Alzheimer disease: a 2020–2023 update

Agent

Company

Synonyms

Therapeutic purpose

ClinicalTrials.gov identifier

Status

ABBV-916

AbbVie

N3pG-Abeta mAb

Immunotherapy (passive)

NCT05291234

Recruiting

ALZ-801

Alzheon

valiltramiprosate

Small molecule

NCT04693520

Active, not recruiting

CT1812 (SHINE (COG0201) Study)

Cognition Therapeutics

Elayta

Small molecule

NCT03507790

Recruiting

CT1812 (START(COG0203) study)

   

NCT05531656

Recruiting

Varoglutamstat (VIVA-MIND)

Vivoryon Therapeutics AG. ADCS. NIA

PQ912

Small molecule

NCT03919162

Recruiting

Varoglutamstat (VIVID)

   

NCT04498650

Active, not recruiting