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Fig. 8 | Journal of Biomedical Science

Fig. 8

From: SCEL regulates switches between pro-survival and apoptosis of the TNF-α/TNFR1/NF-κB/c-FLIP axis to control lung colonization of triple negative breast cancer

Fig. 8

Depletion of SCEL suppresses cell proliferation and induces apoptosis in the lung metastatic loci. A Representative images of immunohistochemistry staining (IHC) for SCEL, CD206, CD68, cleaved caspase 3, Ki67 expression, TNFR1, and TNF-α of the metastatic lung nodules derived mice injected with the control LC and SCEL-downregulated LC cells, respectively. B Quantification of IHC staining of SCEL, CD206, CD68, cleaved caspase 3 and Ki67, TNFR1, and TNF-α expression in the metastatic lung nodules using Image J. *P < 0.05

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Journal of Biomedical Science

ISSN: 1423-0127