Table 3 Several advantages associated with deep sequencing [10]
Advantage | Description |
|---|---|
High-throughput | This technology can effectively sequence millions of DNA fragments in parallel; it generates massive amounts of sequence data during a sample run. As a consequence, it allows for the analysis of entire genomes, transcriptomes, and targeted regions of interest in a single experiment |
Fast | A single NGS run can generate millions to billions of sequences in a matter of hours to days, whereas Sanger sequencing is much slower and labor-intensive |
Cost-effective | It has the ability to sequence a large number of samples simultaneously, where the cost per base of sequence data is dramatically reduced when compared to traditional methods; this makes studies involving genomics and transcriptomics highly affordable |
Accurate | Its current error rates are less than 1% |