Figure 3
From: Investigation on the role of nsSNPs in HNPCC genes – a bioinformatics approach
(A) Native structure of MSH6 gene with 'B' chain of PDB ID 2O8C(orange). (B) Superimposed structure of native tyrosine (orange) with mutant amino acid serine (pale green) at 538 position in 2O8C with RMSD 3.52 Å. (C) Superimposed structure of native serine (orange) with mutant amino acid leucine (pale green) at 580 position in 2O8C with RMSD 3.37 Å. (D)Superimposed structure of native lysine (orange) with mutant amino acid methionine (pale green) at 854 position in 2O8C with RMSD 3.30 Å.