Curcumin modulates dopaminergic receptor, CREB and phospholipase c gene expression in the cerebral cortex and cerebellum of streptozotocin induced diabetic rats

Table 1 Blood glucose (mg/dl) level in Experimental rats

Animal status	0 day (Before STZ injection)	3^rd day (Initial)	6^th day	10^th day	14^th day (Final)
Control	87.2 ± 1.4	86.6 ± 1.2	83.2 ± 1.2	86.3 ± 1.2	85.7 ± 1.5
Diabetic	85.3 ± 1.3	257.3 ± 0.9	318.2 ± 1.6	307.8 ± 1.3	320.5 ± 1.3***
D + I	86.4 ± 0.9	249.8 ± 1.2	303.6 ± 0.8	185.9 ± 1.5	137.0 ± 1.3^{ψψψ ϕϕϕ}
D+C	89.3 ± 1.5	259.7 ± 1.8	305 ± 0.9	190 ± 1.7	175.6 ± 1.0^{ψψψ ϕϕϕ}

Values are mean ± S.E.M of 4-6 rats in each group. Each group consist of 6-8 rats
*** P < 0.001 when compared to control, ^ψψψP < 0.001 when compared to diabetic group, ^ϕϕϕ p < 0.001 when compared with initial reading
D + I- Insulin treated diabetic rats
D+C- Curcumin treated diabetic rats

ISSN: 1423-0127